I’d like to utilise this platform to pose the question as titled, and hopefully stimulate some discussion around alternative methods for the following point…
My specific area of interest is around mechanical properties of injectable materials, as well as host response. These are ‘old questions’ if you like, but remain unanswered. Many of the injectable materials have mechanical properties far inferior to the biological tissues that they replace. The answer to this question, in my opinion, comes down to molecular weight and molecular interactions but many of the processes that turn low molecular weight polymers into high molecular weight (or crosslinked) polymers require highly toxic species (initiators, crosslinkers, etc) but is there a more biologically friendly way of doing this?
I very much look forward to hearing your thoughts.